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Chapter 2 explores how these simple building blocks are joined to form proteins that have unique three-dimensional structures, making them capable of performing specific biologic functions. The chemical nature of this side chain determines the function of an amino acid in a protein, and provides the basis for classification of the amino acids as nonpolar , uncharged polar, acidic, or basic. The label on the line defines the relationship between two concepts, so that it reads as a valid statement, that is, the connection creates meaning. Therefore, the effective concentration of the permeable form of each drug at its absorption site is determined by the relative concentrations of the charged and uncharged forms. Acidosis shifts the oxygen dissociation curve to the left.
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